GlycoErase™ STK40 Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF485)

Description	GlycoErase™ STK40 knockout HEK293 cell line is a HEK293 model lacking STK40 expression. STK40 encodes a predicted Ser/Thr kinase implicated in MAPK cascade regulation and metabolism-linked transcriptional control. Removal of STK40 in the HEK293 system supports dissection of kinase-signaling networks, MAPK-driven transcriptional dynamics, and developmental pathway regulation, with relevance to human respiratory biology and cancer-related metabolic studies.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	STK40
Full Name	Serine/Threonine Kinase 40
Alternative Name	SHIK; SgK495
Location	1p34.3
Gene ID	83931
Summary	Predicted to have ATP binding and serine/threonine kinase activity, with roles in MAPK cascade regulation, glycogen metabolism, and lung and respiratory system development. Localized in cytosol and nucleoplasm.