GlycoErase™ STK40 Knockout CHO-K1 Cell Line

GlycoErase™ STK40 knockout CHO-K1 cell line is a CHO-K1 model in which STK40 expression has been eliminated. STK40 is a predicted serine/threonine kinase implicated in regulation of the MAPK cascade and glycogen-related processes, with cytosolic and nucleoplasmic localization. The knockout provides a tractable platform to dissect kinase signaling networks at the metabolism interface, MAPK-dependent transcriptional control, and developmental pathway regulation relevant to respiratory and metabolic biology.

KO Cell Lines

Hamster

Epithelial, adherent

1:3~1:5

CHO-K1

Chinese hamster ovary

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

FBS & Penicillin/Streptomycin & Proline & RPMI

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

STK40

Serine/Threonine Kinase 40

SHIK; SgK495

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in regulation of MAPK cascade. Predicted to act upstream of or within several processes, including glycogen metabolic process; lung development; and respiratory system process. Located in cytosol and nucleoplasm.