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Recombinant Human CHRDL1 protein (NP_001137453.1) is produced in Glycoengineered Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.