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GlycoErase™ HEK293T ST6GAL2 Knockout Cell Line

CAT#: GLJF-0425-JF477

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Overview Specification Target Information Related Products
Overview
Description
We are pleased to introduce an ST6GAL2 knockout HEK293T cell line, specifically designed to aid in the study of sialylation. This cell line lacks the ST6GAL2-encoded ST6 beta-galactoside alpha-2,6-sialyltransferase 2, an enzyme that catalyzes the transfer of sialic acid to oligosaccharide substrates. Researchers can utilize this model to explore the impact of disrupting ST6GAL2 function on sialylation and related cellular pathways.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293T
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Penicillin/Streptomycin
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
ST6GAL2
Full Name
ST6 Beta-galactoside alpha-2,6-sialyltransferase 2
Alternative Name
SIAT2, KIAA1877, St6GalII
Location
2q12.3
Gene ID
84620
Summary
Sialyltransferase that modifies oligosaccharide substrates; polymorphisms may influence risperidone response in schizophrenia patients.
For Research Use Only.
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