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GlycoErase™ PPP1R16A Knockout HEK293T Cell Line

CAT#: GLJF-0825-JF567

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PPP1R16A knockout HEK293T cell line eliminates PPP1R16A, a MYPT subunit targeting PP1c to myosin substrates. Uniquely, its phosphorylation by PKA activates PP1c. The knockout model is useful for dissecting noncanonical PP1 regulation and cell motility.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293T
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Penicillin/Streptomycin
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PPP1R16A
Full Name
Protein Phosphatase 1 Regulatory Subunit 16A
Alternative Name
MYPT3
Location
8q24.3
Gene ID
84988
Summary
This myosin phosphatase targeting (MYPT) subunit directs PP1c toward myosin light chain substrates. Unlike other MYPT proteins, its phosphorylation by protein kinase A activates PP1c activity.
For Research Use Only.
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