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GlycoFlux™ Human A4GALT Overexpression Glycoengineered Cell

CAT#: GLJF-0925-JF213

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human A4GALT overexpression glycoengineered cell is a stable cell line that constitutively overexpresses A4GALT, generating globotriaosylceramide (Gb3) from lactosylceramide. It supports glycosphingolipid remodeling, modeling of Shiga-toxin/Gb3 receptor interactions, and discovery of inhibitors that modulate raft composition and pathogen adhesion.
Product Type
Overexpression Cell Lines
Cell Line
As requested by the client.
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
A4GALT
Full Name
Alpha 1,4-galactosyltransferase (P1PK blood group)
Alternative Name
A14GALT; P(k); P1; Gb3S
Location
22q13.2
Gene ID
53947
Summary
Catalyzes the transfer of galactose to lactosylceramide, forming globotriaosylceramide, which is associated with the P(k) antigen of the P blood group system.
For Research Use Only.
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