Close
0
Inquiry Basket

There is no product in the shopping cart, buy it!

Hot Products
Monosaccharide Products
Oligosaccharide Products
Polysaccharide Products
Carbohydrate-based Surfactant Products
Blood Group Antigen Products
Glycoprotein Products
Glycopeptide Products
Nucleotide Sugar Products
Glycoprotein Assay Kits
Comprehensive Glycoprotein Reagents
Glycoengineered Cell Products
Glycoengineering Viral Particle Products
Glycolipid Products

GlycoFlux™ Human PPP1R3A Overexpression HepG2 Cell Line

CAT#: GLJF-0925-JF688

Datasheet Request COA
Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human PPP1R3A overexpression HepG2 cell line is a stable cell line engineered to express PPP1R3A, the glycogen-targeting regulatory subunit of protein phosphatase 1 in skeletal muscle. It binds glycogen granules and promotes dephosphorylation of glycogen synthase and phosphorylase kinase, thereby enhancing glycogen synthesis. This system is ideal for research on glycogen metabolism, muscle energy regulation, and metabolic disorders.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:4~1:6
Cell Line
HepG2
Primary Disease
Hepatoblastoma
Lineage
Liver
Lineage Subtype
Hepatoblastoma
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Glutamine
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PPP1R3A
Full Name
Protein Phosphatase 1 Regulatory Subunit 3A
Alternative Name
GM; PP1G; PPP1R3
Location
7q31.1
Gene ID
5506
Summary
In skeletal muscle, glycogen-bound PP1 contains a catalytic unit plus a targeting subunit. This gene encodes the targeting protein that binds glycogen and promotes dephosphorylation of glycogen synthase and phosphorylase kinase.
For Research Use Only.
Online Inquiry
Copyright © Creative Biolabs. All Rights Reserved.