Quantitative Human GPR37 (Glycosylated) Sandwich ELISA Kit

The quantitative human GPR37 (glycosylated) sandwich ELISA kit is designed to detect human G protein coupled receptor 37 (GPR37) levels. GPR37 is an orphan G protein-coupled receptor that has been implicated in neuronal development and neurodegenerative diseases, though its precise endogenous ligand and functions are still under investigation. It may play a role in regulating cell survival and signaling in the nervous system. The kit is suitable for various biological samples such as tissue homogenates, cell lysates. Its sensitivity is 0.125 ng/mL, which can accurately detect low concentrations of GPR37 in the sample.

GPR37

Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution

Tissue homogenates, cell lysates

100 μL

0.125 ng/mL

Quantitative sandwich ELISA

1 ng/mL-10 ng/mL

1 h-5 h

450 nm

Store at 2-8°C for long term storage.

Human

G protein coupled receptor 37

GPR37; G protein coupled receptor 37; EDNRBL; PAELR; Endothelin receptor type B-like; Parkin-associated endothelin receptor-like receptor; Prosaposin receptor GPR37

36, 222, 239

The quantitative human GPR37 (glycosylated) sandwich ELISA kit is valuable for researchers investigating Parkinson's disease, schizophrenia, and other neurological disorders, where GPR37 expression and function are potentially altered. By quantifying GPR37, researchers can gain insights into its role in disease pathogenesis and explore potential therapeutic targets related to neuronal signaling and survival.

Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;

Serum sample: n=5, 85-100%;
Plasma sample: n=4, 80-100%;

The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.