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Recombinant Human ADAMTS13 Protein, Glycoengineered Mannose-5 Pichia pastoris

CAT#: GLJF-0622-JF112

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant human ADAMTS13 protein (NP_620594.1) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites.
Source
Glycoengineered Mannose-5 Pichia pastoris
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
ADAMTS13
Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 13
Gene ID
11093
Uniprot ID
Q76LX8
Accession Number
NP_620594.1
Background
This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.
Alternate Names
ADAM-TS 13; ADAM-TS13; ADAMTS-13; von Willebrand factor-cleaving protease; vWF-CP; vWF-cleaving protease; ADAMTS13; C9orf8; UNQ6102/PRO20085
For Research Use Only.
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