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Recombinant Human C4B protein (NP_001002029.3) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components.