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Recombinant Human CLCA1 protein (NP_001276.2) is produced in Glycoengineered Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
Alternate Names
Chloride Channel Accessory 1; Chloride Channel, Calcium Activated, Family Member 1; Calcium-Activated Chloride Channel Family Member 1; Calcium-Activated Chloride Channel Protein 1; Chloride Channel Regulator 1; HCaCC-1; CaCC-1; HCLCA1; CACC1; CLCA Family Member 1, Chloride Channel Regulator; Calcium-Dependent Chloride Channel-1; EC 3.4.-.-; CLCRG1; CACC; GOB5