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Recombinant Human CRTAC1 protein (NP_001193457.1) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions.