GlycoErase™ HEK293T UGGT2 Knockout Cell Line (CAT#: GLJF-0425-JF487)

Description	We are pleased to introduce a UGGT2 knockout HEK293T cell line, specifically designed to aid in the study of protein folding quality control. This cell line, lacking the UGGT2-encoded UDP-glucose glycoprotein glucosyltransferase 2, offers a valuable tool for researchers to explore the impact of disrupting UGGT2 function on protein folding and quality control processes. By utilizing HEK293T cells, a platform well-suited for gene function and regulation studies, researchers can gain a deeper understanding of the role of UGGT2 in maintaining protein homeostasis.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293T
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	DMEM & FBS & Penicillin/Streptomycin
Application	Functional assay
Size	2 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	UGGT2
Full Name	UDP-glucose glycoprotein glucosyltransferase 2
Alternative Name	MGC150689, HUGT2, FLJ10873, MGC87276, FLJ11485, MGC117360, UGCGL2
Location	13q32.1
Gene ID	55757
Summary	Endoplasmic reticulum protein that reglucosylates unfolded glycoproteins, ensuring quality control for protein transport.