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GlycoErase™ PPP1R35 Knockout Glycoengineered Cell

CAT#: GLJF-0825-JF114

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PPP1R35 knockout glycoengineered cell disrupts a PP1 regulatory protein predicted to inhibit phosphatase activity and regulate centriole elongation. This model enables studies of centrosome biology and cell cycle regulation.
Product Type
KO Cell Lines
Cell Line
As requested by the client.
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PPP1R35
Full Name
Protein Phosphatase 1 Regulatory Subunit 35
Alternative Name
C7orf47
Location
7q22.1
Gene ID
221908
Summary
Predicted to enable phosphatase binding activity and protein phosphatase inhibitor activity. Involved in positive regulation of centriole elongation. Located in centriole and centrosome.
For Research Use Only.
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