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GlycoFlux™ Human AMY1A Overexpression HepG2 Cell Line

CAT#: GLJF-0925-JF612

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human AMY1A overexpression HepG2 cell line is a stable cell line engineered to produce AMY1A, a salivary amylase that hydrolyzes α-1,4-glucosidic bonds in starch and glycogen to initiate carbohydrate digestion. Multiple transcript variants encode the same protein. This system supports research into digestive physiology, enzyme regulation, and carbohydrate metabolism.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:4~1:6
Cell Line
HepG2
Primary Disease
Hepatoblastoma
Lineage
Liver
Lineage Subtype
Hepatoblastoma
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Glutamine
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
AMY1A
Full Name
Amylase Alpha 1A
Alternative Name
AMY1
Location
1p21.1
Gene ID
276
Summary
Amylases are secreted enzymes that hydrolyze 1,4-alpha-glucosidic bonds in starch and glycogen, initiating carbohydrate digestion. Multiple amylase genes are highly expressed in salivary glands or the pancreas. This gene encodes a salivary amylase isoenzyme, with alternative splicing generating multiple transcript variants of the same protein.
For Research Use Only.
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