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GlycoFlux™ Human AMY1A Overexpression HEK293 Cell Line

CAT#: GLJF-0925-JF380

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human AMY1A overexpression HEK293 cell line is a stable glycoengineered line that constitutively overexpresses salivary amylase AMY1A, a secreted, N-glycosylated hydrolase that cleaves 1,4-α-glucosidic bonds to initiate starch/glycogen breakdown. Use it as a secretion and glycoform benchmark to link N-glycan branching/sialylation with enzyme kinetics, thermal stability, and serum half-life in bioprocess-like settings.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & DMEM
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
AMY1A
Full Name
Amylase Alpha 1A
Alternative Name
AMY1
Location
1p21.1
Gene ID
276
Summary
This salivary gland amylase isoenzyme hydrolyzes 1,4-alpha-glucoside bonds in carbohydrates, initiating starch and glycogen digestion. It is part of a gene cluster expressed at high levels in salivary glands or pancreas. Alternative splicing generates identical protein products.
For Research Use Only.
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