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GlycoFlux™ Human PPP1R13L Overexpression HEK293T Cell Line

CAT#: GLJF-0925-JF564

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human PPP1R13L overexpression HEK293T cell line is a stable cell line engineered to express PPP1R13L (IASPP), a conserved inhibitor of p53, in contrast to ASPP1 and ASPP2, which activate p53. As a negative regulator of apoptosis, IASPP is linked to tumorigenesis and cell survival. This model enables investigations into cancer biology, apoptosis resistance, and p53 signaling modulation.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293T
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Penicillin/Streptomycin
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PPP1R13L
Full Name
Protein Phosphatase 1 Regulatory Subunit 13 Like
Alternative Name
RAI; RAI4; ARCME; CMAEA; IASPP; NKIP1
Location
19q13.32
Gene ID
10848
Summary
IASPP is a conserved negative regulator of p53, in contrast to ASPP1 and ASPP2, which activate p53.
For Research Use Only.
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