Specifications Quality Control Target Information Related Products

Specifications

Description

GlycoFlux™ MSCV-PRKACB Viral Particle installs PRKACB catalytic variants for precise control of cAMP signal transduction; MSCV enables genome-integrating, replication-defective transduction in stem/progenitor contexts to maintain persistent expression in stable lines.

Product Type

Recombinant MSCV Retrovirus

Target

PRKACB

Species

Human

Promotor

MSCV 5' LTR promoter

Packaging System

Retrovirus

Packaging Cell

HEK293T

Application

This MSCV vector is a common retroviral vector system used to achieve high-efficiency, stable gene delivery into target cells, such as hematopoietic stem cells. It ensures long-term, sustained expression by stably integrating the gene into the host cell's genome.

Shipping

Dispatched on dry ice with temperature held at or below -80°C.

Storage

Store at -80°C to preserve titer and stability.

Handling Notes

Store at -80°C and avoid repeated freeze-thaw cycles to preserve viral titer. For safety, handle materials in a biological safety cabinet while wearing appropriate PPE (lab coat, gloves, and eye protection).

Product Disclaimer

These products are for research use only and not for diagnostic or clinical use. The user assumes full responsibility for all safety protocols and compliance with relevant regulations. While we are committed to quality, Creative Biolabs makes no guarantee as to the performance of these products in a specific application.

Quality Control

Titer Assay

qPCR

Mycoplasma Test

Negative

Sterility

Sterility testing confirmed no microbial contamination.

Transduction Evaluation

Creative Biolabs offers, upon request, in vitro and in vivo transduction assays to verify lentiviral targeting and to quantify transgene expression and functional output.

Insert Identity Confirmation

All Creative Biolabs retroviral vectors undergo PCR-based verification of proviral integration. Cells are transduced across a dilution series of the retroviral preparation; after several days, genomic DNA is isolated, and a defined region of the expected insert is PCR-amplified to confirm correct identity and integration.

Target Information

Full Name

Protein Kinase Camp-Activated Catalytic Subunit Beta

Alternative Name

CAFD2; PKACB; PKA C-beta

Location

1p31.1

Gene ID

5567

Summary

The encoded protein is a catalytic chain of PKA that transduces cAMP signals to regulate proliferation, differentiation, and other cellular processes. Several alternatively spliced variants produce distinct isoforms.

GlycoFlux™ MMLV-Human PRKACB Viral Particle (CAT#: GLJF-1025-JF500)
GlycoFlux™ AAV1-Human PRKACB Viral Particle (CAT#: GLJF-1025-JF1014)
GlycoFlux™ Lenti-Human PRKACB Viral Particle (CAT#: GLJF-1025-JF243)

GlycoFlux™ MSCV-Human PRKACB Viral Particle