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Quantitative Human CHRN α1 (Glycosylated) Sandwich ELISA Kit (CAT#: GLJF-0525-HX155)

Datasheet
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1×48 T
1×96 T

Product Description The quantitative human CHRN α1 (glycosylated) sandwich ELISA kit is designed to detect human cholinergic receptor, nicotinic α1 (CHRN α1) levels. CHRN α1 is a subunit of the nicotinic acetylcholine receptor (nAChR), a ligand-gated ion channel crucial for neuromuscular transmission. It plays a key role in muscle contraction and is targeted in autoimmune diseases like myasthenia gravis. The kit is suitable for various biological samples such as tissue homogenates, cell lysates. Its sensitivity is 0.501 ng/mL, which can accurately detect low concentrations of CHRN α1 in the sample.
Target CHRN α1
N-Glycosylation Site 161
Sample Types Tissue homogenates, cell lysates
Sample Volume 100 μL
Sensitivity 0.501 ng/mL
Detection Principle Quantitative sandwich ELISA
Detection Range 2.25 ng/mL-50 ng/mL
Detection Time 1 h-5 h
Detection Wavelength 450 nm
Storage Store at 2-8°C for long term storage.
Species Human
Full Name Cholinergic receptor, nicotinic α1
Alternate Names CHRN α1; Cholinergic receptor, nicotinic α1; CHR-NA1; NAChRA1; ACHRD; CMS2A; SCCMS; Acetylcholine receptor subunit α
Uniprot No. P02708
Application The quantitative human CHRN α1 (glycosylated) sandwich ELISA kit is valuable in research investigating neuromuscular disorders, myasthenia gravis, and the effects of nicotinic receptor agonists or antagonists. Researchers utilize this ELISA to quantify CHRNα1 levels, providing insights into its role in neuromuscular function and related pathologies.
Kit Components Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Precision Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;
Recovery Serum sample: n=5, 90-105%;
Plasma sample: n=4, 85-100%;
Standard Curve
The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.
For Research Use Only.
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