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Recombinant Human BMP3 Protein, Glycoengineered Mannose-5 Pichia pastoris

CAT#: GLJF-0722-JF205

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Human BMP3 protein (NP_001192.3) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites.
Source
Glycoengineered Mannose-5 Pichia pastoris
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
BMP3
Full Name
Bone morphogenetic protein 3
Gene ID
651
Uniprot ID
P12645
Accession Number
NP_001192.3
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
Alternate Names
BMP3; BMP3A
For Research Use Only.
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