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Recombinant Human COL6A1 Protein, Sia-Increased Human Cell Lines

CAT#: GLJF-0722-JF697

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Specifications
Product Overview
Recombinant Human COL6A1 protein (NP_001839.2) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Source
Sia-Increased Human Cell Lines
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
COL6A1
Full Name
Collagen alpha-1(VI) chain
Gene ID
Accession Number
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Alternate Names
Collagen, Type VI, Alpha 1; Collagen VI, Alpha-1 Polypeptide; Alpha 1 (VI) Chain (61 AA); OPLL
For Research Use Only.
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