Recombinant Human COMP Protein, Glycoengineered Pichia pastoris (CAT#: GLJF-0722-JF49)

Product Overview	Recombinant Human COMP protein (NP_000086.2) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
Source	Glycoengineered Pichia pastoris
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	COMP
Full Name	Cartilage oligomeric matrix protein
Gene ID	1311
Uniprot ID	P49747
Accession Number	NP_000086.2
Background	The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Alternate Names	Cartilage Oligomeric Matrix Protein; Thrombospondin-5; Cartilage Oligomeric Matrix Protein (Pseudoachondroplasia, Epiphyseal Dysplasia 1, Multiple); TSP5; Cartilage Oligomeric Matrix Protein(Pseudoachondroplasia, Epiphyseal Dysplasia 1, Multiple); Pseudoachondroplasia (Epiphyseal Dysplasia 1, Multiple); THBS5; PSACH; EDM1; EPD1; MED