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Recombinant Human DMBT1 protein (NP_001307573.1) is produced in Fuco-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degree.
This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition.