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Recombinant Human FLT3LG protein (NP_001191431.1) is produced in Sia-Adjusted Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with different sialylation degrees.
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts.