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Recombinant Human FLT3LG protein (NP_001191431.1) is produced in Glycoengineered Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts.