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Recombinant Human GDF15 protein (NP_004855.2) is produced in Glycoengineered Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury.