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Recombinant Human GDF15 protein (NP_004855.2) is produced in Sia-Increased Human Cell Line. This expression system is used for the production of glycoproteins with high sialylation with fucosylation.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury.