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Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 (GP2) (22-531 aa) [6xHis-SUMO-tag], E. coli (CAT#: GPX04-298J)

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1 mg
500 μg
100 μg

Product Overview Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 (NP_080265.2) (22-531 aa) was expressed in E. coli with a 6xHis-SUMO-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity Determined by its binding ability in a functional ELISA.
Source E. coli
Species Mouse
Fragment 22-531 aa
Sequence STIHQGYGRPRNSSNLDLDCGSPDSPSSGICFDPCQNHTVLNDPTRSTENNDSSVAWCDDNLHGWYRFVGDGGVKMPETCVSVFRCHTSAPMWLSGSHPILGDGIVSHTACANWNENCCFWRSEVQVKACSEELGEYHVYKLQGTPECSLRYCTDPSTAPKNCEITCRPEEECVFQNNNWSCVCRQDLHVSDSQSLQPLLDCGDNEIKVKLDKCLLGGMGFKEEIIAYLNDRNCNGTMQDEPNNWVSMTSPVVANYCGNILEKNGTHAIYRNTLSLATDFIIRDFRVNVNFQCAYPLDMSVSLETALQPIVSSLTVDVDGAGEFNVKMALFQDQSYTNPYEGAEVLLPVESILYVGVLLNRGDTSRFKLLLTNCYATPSEDRHDPVKYFIIKNRCPNQRDSTINVRENGVSSESRFSVQMFMFAGNYDLVFLHCEVYLCDSTTEQCQPSCSTNRLRSSRPAIDYNRVLDLGPITKRSAQSSATSKGTPHTTGFLLAWPMFFLPVFLALLF
Tag 6xHis-SUMO-tag at the N-terminus
Predicted MW 73.0 kDa
Purity >90%, determined by SDS-PAGE.
Conjugation Unconjugated
Target GP2
Full Name Pancreatic secretory granule membrane major glycoprotein GP2
Gene ID 67133
Uniprot ID Q9D733
Accession Number NP_080265.2
Background Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participates to the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.
Alternate Names Pancreatic zymogen granule membrane protein GP-2; Gp2
For Research Use Only.
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