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GlycoErase™ AMY2B Knockout Glycoengineered Cell

CAT#: GLJF-0825-JF10

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ AMY2B knockout glycoengineered cell disrupts pancreatic amylase, an enzyme that hydrolyzes 1,4-alpha-glucoside bonds in polysaccharides and catalyzes the initial step in dietary starch and glycogen digestion. This model supports research on pancreatic enzyme activity and carbohydrate metabolism.
Product Type
KO Cell Lines
Cell Line
As requested by the client.
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
AMY2B
Full Name
Amylase Alpha 2B
Alternative Name
HXA; AMY2; AMY3
Location
1p21.1
Gene ID
280
Summary
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.
For Research Use Only.
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