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GlycoErase™ FUT7 Knockout Human Lung Cancer Cell A-427

CAT#: GLJF-0525-JF1304

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Overview Specification Target Information Related Products
Overview
Description
The FUT7 knockout A-427 cell line, also involved in sialyl-Lewis X synthesis, similar to FUT6 knockout, allows for the study of sialyl-Lewis X's role in lung adenocarcinoma cell adhesion, metastasis, and E-selectin ligand presentation, potentially revealing redundant or distinct functions of FUT6 and FUT7.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:3
Cell Line
A-427
Primary Disease
Non-Small Cell Lung Cancer
Lineage
Lung
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
FUT7
Full Name
Fucosyltransferase 7
Alternative Name
Alpha-1,3-fucosyltransferase 7, Fucosyltransferase FucT-VI, FucT-VI
Location
9q34.3
Gene ID
2529
Summary
Golgi membrane protein responsible for the creation of sialyl-Lewis X antigens, which play a role in leukocyte trafficking and inflammation.
For Research Use Only.
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