GlycoErase™ GPHA2 Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF401)

Description	GlycoErase™ GPHA2 knockout HEK293 cell line is a human embryonic kidney (HEK293) model with GPHA2 expression removed. GPHA2 encodes a cystine knot-forming polypeptide that functions as a subunit of dimeric glycoprotein hormones. This knockout HEK293 model supports studies of glycoprotein hormone assembly, receptor binding, and hormone signaling, providing a valuable system for research in endocrinology, reproductive biology, and glycoprotein therapeutic development.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	GPHA2
Full Name	Glycoprotein Hormone Subunit Alpha 2
Alternative Name	A2; GPA2; ZSIG51
Location	11q13.1
Gene ID	170589
Summary	GPHA2 is a cystine knot-containing subunit of dimeric glycoprotein hormones.