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GlycoErase™ PPP1R3F Knockout Glycoengineered Cell

CAT#: GLJF-0825-JF104

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PPP1R3F knockout glycoengineered cell disrupts a PP1 regulatory subunit that modulates substrate specificity and localization within PP1 holoenzymes. This model is useful for investigating PP1 signaling and compartment-specific phosphatase activity.
Product Type
KO Cell Lines
Cell Line
As requested by the client.
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PPP1R3F
Full Name
Protein Phosphatase 1 Regulatory Subunit 3F
Alternative Name
R3F; HB2E; LL0XNC01-7P3.1
Location
Xp11.23
Gene ID
89801
Summary
This gene encodes a protein that has been identified as one of several type-1 protein phosphatase (PP1) regulatory subunits. One or two of these subunits, together with the well-conserved catalytic subunit, can form the PP1 holoenzyme, where the regulatory subunit functions to regulate substrate specificity and/or targeting to a particular cellular compartment. Alternative splicing results in multiple transcript variants.
For Research Use Only.
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