Close
0
Inquiry Basket

There is no product in the shopping cart, buy it!

Hot Products
Monosaccharide Products
Oligosaccharide Products
Polysaccharide Products
Carbohydrate-based Surfactant Products
Blood Group Antigen Products
Glycoprotein Products
Glycopeptide Products
Nucleotide Sugar Products
Glycoprotein Assay Kits
Comprehensive Glycoprotein Reagents
Glycoengineered Cell Products
Glycoengineering Viral Particle Products
Glycolipid Products

GlycoErase™ PRDM8 Knockout HEK293 Cell Line

CAT#: GLJF-0825-JF469

Datasheet Request COA
Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PRDM8 knockout HEK293 cell line is a HEK293 model lacking PRDM8, a SET-domain histone methyltransferase that represses transcription and interacts with laforin/malin complexes linked to glycogen regulation. This knockout supports epigenetic mechanism research, human neuronal pathway modeling, and studies of chromatin-metabolism cross-talk with relevance to neurodegeneration and metabolic disorders.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PRDM8
Full Name
Pr/Set Domain 8
Alternative Name
PFM5; EPM10; KMT8D
Location
4q21.21
Gene ID
56978
Summary
This gene encodes a histone methyltransferase with SET and zinc-finger domains that acts mainly as a transcriptional repressor. It interacts with laforin and malin, influencing glycogen metabolism. Alternative transcripts are known.
For Research Use Only.
Online Inquiry
Copyright © Creative Biolabs. All Rights Reserved.