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GlycoErase™ STT3A Knockout Human Renal Cell Adenocarcinoma Cell 769-P

CAT#: GLJF-0525-JF484

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Overview Specification Target Information Related Products
Overview
Description
The STT3A deficient human renal cell adenocarcinoma cell 769-P line, lacking STT3A protein essential for N-glycosylation, allows investigation of N-linked glycosylation disruption in renal cell adenocarcinoma, impacting cell surface receptor signaling, protein folding, and immune-related functions within the tumor context.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:4~1:12
Cell Line
769-P
Primary Disease
Renal Cell Carcinoma
Lineage
Kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
Glutamine & NaHCO₃ & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
STT3A
Full Name
STT3 oligosaccharyltransferase complex catalytic subunit A
Location
11q24.2
Gene ID
3703
Summary
Catalytic subunit of the N-oligosaccharyltransferase (OST) complex, responsible for transferring glycan chains to asparagine residues of target proteins in the endoplasmic reticulum.
For Research Use Only.
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