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GlycoFlux™ MSCV-Human PTGER4 Viral Particle (CAT#: GLJF-1025-JF759)

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Description GlycoFlux™ MSCV-PTGER4 Viral Particle implements PTGER4 (PGE2 receptor) to probe TCF activation, EGR1 induction, COX-2 mRNA stability, and GSK3 phosphorylation; MSCV furnishes stable, genome-integrating delivery under a replication-defective safety design for long-term lines.
Product Type Recombinant MSCV Retrovirus
Target PTGER4
Species Human
Promotor MSCV 5' LTR promoter
Packaging System Retrovirus
Packaging Cell HEK293T
Application This MSCV vector is a common retroviral vector system used to achieve high-efficiency, stable gene delivery into target cells, such as hematopoietic stem cells. It ensures long-term, sustained expression by stably integrating the gene into the host cell's genome.
Shipping Dispatched on dry ice with temperature held at or below -80°C.
Storage Store at -80°C to preserve titer and stability.
Handling Notes Store at -80°C and avoid repeated freeze-thaw cycles to preserve viral titer. For safety, handle materials in a biological safety cabinet while wearing appropriate PPE (lab coat, gloves, and eye protection).
Product Disclaimer These products are for research use only and not for diagnostic or clinical use. The user assumes full responsibility for all safety protocols and compliance with relevant regulations. While we are committed to quality, Creative Biolabs makes no guarantee as to the performance of these products in a specific application.
Titer Assay qPCR
Mycoplasma Test Negative
Sterility Sterility testing confirmed no microbial contamination.
Transduction Evaluation Creative Biolabs offers, upon request, in vitro and in vivo transduction assays to verify lentiviral targeting and to quantify transgene expression and functional output.
Insert Identity Confirmation All Creative Biolabs retroviral vectors undergo PCR-based verification of proviral integration. Cells are transduced across a dilution series of the retroviral preparation; after several days, genomic DNA is isolated, and a defined region of the expected insert is PCR-amplified to confirm correct identity and integration.
Full Name Prostaglandin E Receptor 4
Alternative Name EP4; EP4R
Location 5p13.1
Gene ID 5734
Summary This gene produces a G-protein coupled receptor that serves as one of four prostaglandin E2 (PGE2) receptors. It participates in T-cell factor activation, promotes EGR1 expression, stabilizes cyclooxygenase-2 mRNA, and induces glycogen synthase kinase-3 phosphorylation. Mouse models indicate roles in circulatory adaptation after birth, bone metabolism, and skin immune initiation.
For Research Use Only.
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