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Quantitative Human C1R (Glycosylated) Sandwich ELISA Kit

CAT#: GLJF-0525-HX130

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Specifications
Product Description
The quantitative human C1R (glycosylated) sandwich ELISA kit is designed to detect human complement component 1, R subcomponent (C1R) levels. C1R is a serine protease involved in the classical pathway of the complement system, a crucial part of the innate immune response. It initiates the complement cascade by cleaving C1s upon activation by antibody-antigen complexes. The kit is suitable for various biological samples such as serum, plasma. Its sensitivity is 1.598 ng/mL, which can accurately detect low concentrations of C1R in the sample.
Target
C1R
Kit Components
Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Sample Types
Serum, plasma
Sample Volume
100 μL
Sensitivity
1.598 ng/mL
Detection Principle
Quantitative sandwich ELISA
Detection Range
5 ng/mL-200 ng/mL
Detection Time
1 h-5 h
Detection Wavelength
450 nm
Storage
Store at 2-8°C for long term storage.
Target Information
Species
Human
Full Name
Complement component 1, R subcomponent
Alternate Names
C1R; Complement component 1, R subcomponent
Uniprot No.
N-Glycosylation Site
125, 221, 514, 581
Application Notes
Application
The quantitative human C1R (glycosylated) sandwich ELISA kit is utilized in research settings to investigate the role of C1R in immune responses, autoimmune diseases, and inflammatory conditions. Researchers use this ELISA to quantify C1R levels, providing insights into its involvement in various physiological and pathological processes related to complement activation.
Precision
Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;
Recovery
Serum sample: n=5, 80-95%;
Plasma sample: n=4, 85-100%;
Standard Curve

The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.
For Research Use Only.
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