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The quantitative human C1R (glycosylated) sandwich ELISA kit is designed to detect human complement component 1, R subcomponent (C1R) levels. C1R is a serine protease involved in the classical pathway of the complement system, a crucial part of the innate immune response. It initiates the complement cascade by cleaving C1s upon activation by antibody-antigen complexes. The kit is suitable for various biological samples such as serum, plasma. Its sensitivity is 1.598 ng/mL, which can accurately detect low concentrations of C1R in the sample.
The quantitative human C1R (glycosylated) sandwich ELISA kit is utilized in research settings to investigate the role of C1R in immune responses, autoimmune diseases, and inflammatory conditions. Researchers use this ELISA to quantify C1R levels, providing insights into its involvement in various physiological and pathological processes related to complement activation.