Quantitative Human ROS1 (Glycosylated) Sandwich ELISA Kit

The quantitative human ROS1 (glycosylated) sandwich ELISA kit is designed to detect human c-ros oncogene 1, receptor tyrosine kinase (ROS1) levels. ROS1 is a receptor tyrosine kinase involved in cell growth and differentiation, and its aberrant activation through gene fusions is implicated in various cancers. It plays a role in normal development and tissue homeostasis. The kit is suitable for various biological samples such as tissue homogenates, serum, plasma. Its sensitivity is 0.078 ng/mL, which can accurately detect low concentrations of ROS1 in the sample.

ROS1

Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution

Tissue homogenates, serum, plasma

100 μL

0.078 ng/mL

Quantitative sandwich ELISA

1 ng/mL-10 ng/mL

1 h-5 h

450 nm

Store at 2-8°C for long term storage.

Human

C-ros oncogene 1, receptor tyrosine kinase

ROS1; C-ros oncogene 1, receptor tyrosine kinase; MCF3; ROS; Sarcoma virus oncogene homolog 1

52, 114, 123, 324, 352, 396, 471, 607, 628, 706, 714, 732, 939, 961, 1015, 1087, 1090, 1095, 1211, 1272, 1330, 1458, 1461, 1474, 1499, 1565, 1669, 1715, 1738, 1808

The quantitative human ROS1 (glycosylated) sandwich ELISA kit is valuable in research investigating cancer diagnostics and personalized medicine, particularly for identifying patients with ROS1-positive tumors who may benefit from targeted therapies. Researchers utilize this ELISA to quantify ROS1 levels, providing insights into its expression and potential therapeutic applications in oncology.

Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;

Serum sample: n=5, 85-105%;
Plasma sample: n=4, 90-105%;

The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.