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Quantitative Human ROS1 (Glycosylated) Sandwich ELISA Kit (CAT#: GLJF-0525-HX210)

Datasheet
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1×48 T
1×96 T

Product Description The quantitative human ROS1 (glycosylated) sandwich ELISA kit is designed to detect human c-ros oncogene 1, receptor tyrosine kinase (ROS1) levels. ROS1 is a receptor tyrosine kinase involved in cell growth and differentiation, and its aberrant activation through gene fusions is implicated in various cancers. It plays a role in normal development and tissue homeostasis. The kit is suitable for various biological samples such as tissue homogenates, serum, plasma. Its sensitivity is 0.078 ng/mL, which can accurately detect low concentrations of ROS1 in the sample.
Target ROS1
N-Glycosylation Site 52, 114, 123, 324, 352, 396, 471, 607, 628, 706, 714, 732, 939, 961, 1015, 1087, 1090, 1095, 1211, 1272, 1330, 1458, 1461, 1474, 1499, 1565, 1669, 1715, 1738, 1808
Sample Types Tissue homogenates, serum, plasma
Sample Volume 100 μL
Sensitivity 0.078 ng/mL
Detection Principle Quantitative sandwich ELISA
Detection Range 1 ng/mL-10 ng/mL
Detection Time 1 h-5 h
Detection Wavelength 450 nm
Storage Store at 2-8°C for long term storage.
Species Human
Full Name C-ros oncogene 1, receptor tyrosine kinase
Alternate Names ROS1; C-ros oncogene 1, receptor tyrosine kinase; MCF3; ROS; Sarcoma virus oncogene homolog 1
Uniprot No. P08922
Application The quantitative human ROS1 (glycosylated) sandwich ELISA kit is valuable in research investigating cancer diagnostics and personalized medicine, particularly for identifying patients with ROS1-positive tumors who may benefit from targeted therapies. Researchers utilize this ELISA to quantify ROS1 levels, providing insights into its expression and potential therapeutic applications in oncology.
Kit Components Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Precision Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;
Recovery Serum sample: n=5, 85-105%;
Plasma sample: n=4, 90-105%;
Standard Curve
The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.
For Research Use Only.
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