0
Inquiry Basket

There is no product in the shopping cart, buy it!

Quantitative Human TPP1 (Glycosylated) Sandwich ELISA Kit (CAT#: GLJF-0525-HX27)

Datasheet
SizeQtyAdd To Basket
1×48 T
1×96 T

Product Description The quantitative human TPP1 (glycosylated) sandwich ELISA kit is designed to detect human tripeptidyl peptidase 1 (TPP1) levels. TPP1 is a lysosomal enzyme that plays a crucial role in the degradation of peptides, particularly in neuronal cells. It is essential for lysosomal function and the proper turnover of intracellular proteins. The kit is suitable for various biological samples such as tissue homogenates, cell lysates. Its sensitivity is 0.125 ng/mL, which can accurately detect low concentrations of TPP1 in the sample.
Target TPP1
N-Glycosylation Site 210, 222, 286, 313, 443
Sample Types Tissue homogenates, cell lysates
Sample Volume 100 μL
Sensitivity 0.125 ng/mL
Detection Principle Quantitative sandwich ELISA
Detection Range 1 ng/mL-10 ng/mL
Detection Time 1 h-5 h
Detection Wavelength 450 nm
Storage Store at 2-8°C for long term storage.
Species Human
Full Name Tripeptidyl peptidase 1
Alternate Names TPP1; Tripeptidyl peptidase 1; CLN2; LPIC; Lysosomal pepstatin-insensitive protease
Uniprot No. O14773
Application The quantitative human TPP1 (glycosylated) sandwich ELISA kit is valuable for researchers investigating neuronal ceroid lipofuscinosis (NCL), a lysosomal storage disorder caused by TPP1 deficiency. By quantifying TPP1, researchers can gain insights into disease pathogenesis, monitor disease progression, and evaluate potential therapeutic interventions, such as enzyme replacement therapy.
Kit Components Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Precision Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;
Recovery Serum sample: n=5, 80-100%;
Plasma sample: n=4, 85-100%;
Standard Curve
The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.
For Research Use Only.
Online Inquiry
Creative Biolabs-Glycoprotein Follow us on
  • ()
    ()
    ()
ISO 9001 Certified - Creative Biolabs Quality Management System.
Close
Thanksgiving
Thanksgiving