Recombinant Human ARTN Protein, Fuco-Adjusted Human Cell Lines

Recombinant human ARTN protein (NP_001129687.1) is produced in Fuco-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degree.

Fuco-Adjusted Human Cell Lines

Human

His-tag, FC-tag

>90%, determined by SDS-PAGE.

Regular batch

None

ARTN

Artemin

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Enovin; Neublastin; ARTN; EVN