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Recombinant Human CD59 glycoprotein (CD59) (26-102 aa) [GST-tag], E. coli

CAT#: GPX04-133J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Human CD59 glycoprotein (NP_000602.1) (26-102 aa) was expressed in E. coli with a GST-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
E. coli
Species
Human
Fragment
26-102 aa
Sequence
LQCYNCPNPTADCKTAVNCSSDFDACLITKAGLQVYNKCWKFEHCNFNDVTTRLRENELTYYCCKKDLCNFNEQLEN
Tag
GST-tag at the N-terminus
Predicted MW
36.0 kDa
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
CD59
Full Name
CD59 glycoprotein
Gene ID
966
Uniprot ID
P13987
Accession Number
NP_000602.1
Background
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Alternate Names
1F5 antigen; 20 kDa homologous restriction factor; MAC-inhibitory protein; MEM43 antigen; Membrane attack complex inhibition factor
For Research Use Only.
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