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Recombinant Human COL16A1 protein (NP_001847.3) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.