Recombinant Human CPB2 Protein, Glycoengineered Pichia pastoris

Recombinant Human CPB2 protein (NP_001265470.1) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.

Glycoengineered Pichia pastoris

Human

His-tag, FC-tag

>90%, determined by SDS-PAGE.

Regular batch

None

CPB2

Carboxypeptidase B2

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.

Carboxypeptidase B2 (Plasma); Carboxypeptidase B2 (Plasma, Carboxypeptidase U); Thrombin-Activatable Fibrinolysis Inhibitor; Thrombin-Activable Fibrinolysis Inhibitor; Plasma Carboxypeptidase B; Carboxypeptidase U; Carboxypeptidase R; EC 3.4.17.20; PCPB; TAFI; CPU; Carboxypeptidase B-Like Protein; EC 3.4.17