Recombinant Human CPB2 Protein, Sia-Adjusted Human Cell Lines (CAT#: GLJF-0722-JF830)

Product Overview	Recombinant Human CPB2 protein (NP_001265470.1) is produced in Sia-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different sialylation degree.
Source	Sia-Adjusted Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	CPB2
Full Name	Carboxypeptidase B2
Gene ID	1361
Uniprot ID	Q96IY4
Accession Number	NP_001265470.1
Background	Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.
Alternate Names	Carboxypeptidase B2 (Plasma); Carboxypeptidase B2 (Plasma, Carboxypeptidase U); Thrombin-Activatable Fibrinolysis Inhibitor; Thrombin-Activable Fibrinolysis Inhibitor; Plasma Carboxypeptidase B; Carboxypeptidase U; Carboxypeptidase R; EC 3.4.17.20; PCPB; TAFI; CPU; Carboxypeptidase B-Like Protein; EC 3.4.17