Recombinant Mouse Platelet glycoprotein VI (GP6) (22-265 aa) [6xHis-SUMO-tag], E. coli (CAT#: GPX04-296J)

Product Overview	Recombinant Mouse Platelet glycoprotein VI (NP_001156486.1) (22-265 aa) was expressed in E. coli with a 6xHis-SUMO-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	E. coli
Species	Mouse
Fragment	22-265 aa
Sequence	QSGPLPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEKYEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFDEFVLYKEGDTGSYKRPEKWYRANFPIITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVLVVTGLSATPSQVPTEESFPVTESSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAK
Tag	6xHis-SUMO-tag at the N-terminus
Predicted MW	43.0 kDa
Purity	>90%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	GP6
Full Name	Platelet glycoprotein VI
Gene ID	243816
Uniprot ID	P0C191
Accession Number	NP_001156486.1
Background	Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.
Alternate Names	GPVI; Gp6