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Recombinant Mouse Platelet glycoprotein VI (GP6) (22-313 aa), E. coli

CAT#: GPX04-315J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Mouse Platelet glycoprotein VI (NP_001156486.1) (22-313 aa) was expressed in E. coli with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
E. coli
Species
Mouse
Fragment
22-313 aa
Sequence
QSGPLPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEKYEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFDEFVLYKEGDTGSYKRPEKWYRANFPIITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVLVVTGLSATPSQVPTEESFPVTESSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAKGNLVRICLGATIIIILLGLLAEDWHSRKKCLQHRMRALQRPLPPLPLA
Tag
His-tag or Tag free
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
GP6
Full Name
Platelet glycoprotein VI
Gene ID
243816
Uniprot ID
P0C191
Accession Number
NP_001156486.1
Background
Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.
Alternate Names
GPVI; Gp6
For Research Use Only.
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