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Recombinant Zaire ebolavirus (strain Kikwit-95) Pre-small/secreted glycoprotein (GP) (33-364 aa) [6xHis-tag], Yeast (CAT#: GPX04-463J)

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1 mg
500 μg
100 μg

Product Overview Recombinant Zaire ebolavirus (strain Kikwit-95) Pre-small/secreted glycoprotein (NP_066247.1) (33-364 aa) was expressed in Yeast with a 6xHis-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity Determined by its binding ability in a functional ELISA.
Source Yeast
Species Zaire ebolavirus (strain Kikwit-95)
Fragment 33-364 aa
Sequence IPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKTSLEKFAVKSCLSQLYQTEPKTSVVRVRRELLPTQGPTQQLKTTKSWLQKIPLQWFKCTVKEGKLQCRI
Tag 6xHis-tag at the N-terminus
Predicted MW 39.3 kDa
Purity >90%, determined by SDS-PAGE.
Conjugation Unconjugated
Target GP
Full Name Pre-small/secreted glycoprotein
Gene ID 911829
Uniprot ID P60171
Accession Number NP_066247.1
Background sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils.
Alternate Names pre-sGP; sGP; GP
For Research Use Only.
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