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GlycoErase™ CPT2 Knockout Glycoengineered Cell

CAT#: GLJF-0825-JF12

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ CPT2 knockout glycoengineered cell removes carnitine palmitoyltransferase 2, a mitochondrial protein required for long-chain fatty acid oxidation in cooperation with CPT1. Defects in CPT2 cause LCFA oxidation disorders. This model enables studies of fatty acid metabolism and mitochondrial disease.
Product Type
KO Cell Lines
Cell Line
As requested by the client.
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
CPT2
Full Name
Carnitine Palmitoyltransferase 2
Alternative Name
CPT1; IIAE4; CPTASE
Location
1p32.3
Gene ID
1376
Summary
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
For Research Use Only.
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