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GlycoErase™ HEK293F-ΔSTT3B Cell Line

CAT#: GLJF-0425-JF357

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Overview Specification Target Information Related Products
Overview
Description
This STT3B knockout (HEK293F) cell line lacks the STT3B protein, a STT3 oligosaccharyltransferase complex catalytic subunit B. The protein encoded by this gene is a catalytic subunit of a protein complex that transfers oligosaccharides onto asparagine residues. Defects in this gene are a cause of congenital disorder of glycosylation type Ip. Loss of STT3B function may cause congenital disorders of glycosylation.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293F
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
STT3B
Full Name
STT3 oligosaccharyltransferase complex catalytic subunit B
Alternative Name
SIMP, STT3-B, FLJ90106
Location
3p23
Gene ID
201595
Summary
Catalytic subunit of a protein complex that transfers oligosaccharides to asparagine residues; defects cause congenital disorder of glycosylation Ix (CDG1X).
For Research Use Only.
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