GlycoErase™ HEK293T A4GALT Knockout Cell Line

We are pleased to offer an A4GALT knockout HEK293T cell line, a valuable resource for researchers investigating P(k) antigen synthesis within the P blood group system. This cell line, deficient in the A4GALT-encoded alpha 1,4-galactosyltransferase, allows for controlled experiments to study the impact of disrupting P(k) antigen expression on cellular processes and potential implications for blood group incompatibility. The availability of this knockout in HEK293T cells, a platform widely used for gene function and regulation studies, further enhances its utility for researchers.

KO Cell Lines

Human

Epithelial-like, adherent

1:2~1:4

HEK293T

Embryonic kidney

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

DMEM & FBS & Penicillin/Streptomycin

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

A4GALT

Alpha 1,4-galactosyltransferase (P1PK blood group)

A14GALT, P(k), P1, Gb3S

22q13.2

Catalyzes the transfer of galactose to lactosylceramide, forming globotriaosylceramide, which is associated with the P(k) antigen of the P blood group system.