GlycoErase™ HEK293T UGT8 Knockout Cell Line (CAT#: GLJF-0425-JF490)

Description	For researchers exploring galactocerebroside biosynthesis, we are pleased to offer a UGT8 knockout HEK293T cell line. This cell line, deficient in the UGT8-encoded UDP-glycosyltransferase, provides a unique opportunity to study the biosynthesis of galactocerebrosides, which are essential components of the myelin sheath. This model, within the context of HEK293T cells, a platform widely used for gene function and regulation studies, allows for in-depth analysis of UGT8's contribution to myelin formation and function.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293T
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	DMEM & FBS & Penicillin/Streptomycin
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	UGT8
Full Name	UDP glycosyltransferase 8
Alternative Name	CGT
Location	4q26
Gene ID	7368
Summary	Catalyzes the transfer of galactose to ceramide, a crucial step in the biosynthesis of galactocerebrosides, essential components of myelin.